WebJun 15, 2024 · The intervention was 33°C for both the TTM and TTM2 trials. Similarly, a normothermic strategy was a applied as the comparator in both trials: a target … Webthe primary and secondary outcomes in the TTM2 trial. Methods The design of the TTM2 trial has been described in de-tail previously [3]. In short, the trial population will be adults …

CAPITAL CHILL... on the hypothermia - First10EM

WebThe recent TTM2 trial is the largest thus far and conclusively showed that, ... Nevertheless, we must keep our cool and stick to the current recommendations on temperature management after cardiac arrest and target normothermia and … WebTargeted Cooling Management per local protocols: Set to target 36C if this is the local protocol. Aggressive fever avoidance (targeting <37.8) if this is the local protocol. (Do not cool into 33C.) Avoid long-acting sedatives that may obscure neuroprognostication (e.g., benzodiazepines, opioids). Propofol is mostly the agent out choice initially. church in hampstead

Hypoxic Brain Injury - StatPearls - NCBI Bookshelf / Cell damage ...

WebNov 15, 2024 · Methods: The TTM2-trial is an international, multicenter, parallel group, investigator-initiated, randomized, superiority trial in which a target temperature of 33°C after cardiac arrest will be ... WebSep 23, 2024 · Dankiewicz et al. (TTM2 Trial Investigators) In an open-label randomized controlled trial with blinded assessment of outcomes, 1900 adults with coma who had had an out-of-hospital cardiac arrest of presumed cardiac or unknown cause were randomized to undergo targeted hypothermia at 33°C, followed by controlled rewarming, or targeted … WebApr 12, 2024 · Using external cooling devices inevitably increase the treatment costs as compared with simple conservative measures. 2 Interestingly, while our strict fever … devotionals on productiveness