Cyp2b10 gene card
WebOn the other hand, progesterone and androgens repressed NR1 activity in HepG2 cells, and the repressed NR1 activity was fully restored by estradiol. Moreover, estrogen treatment elicited nuclear accumulation of CAR in the mouse livers, as well as primary hepatocytes, and induced the endogenous Cyp2b10 gene. WebNov 23, 2024 · Expression of CYP2B10 is known to be regulated by a number of nuclear receptors such as pregnane X receptor (PXR), constitutive androstane receptor (CAR), glucocorticoid receptors (GR), and vitamin D receptor (VDR) ( Beigneux et al., 2002; Pascussi et al., 2004 ). Period 2 (PER2) is a central component of the mammalian …
Cyp2b10 gene card
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WebMar 24, 2011 · We found Cyp2b10, a known CAR target, to be concomitantly hypomethylated and activated in a tissue-specific manner following PB treatment and … WebNov 25, 2016 · Because the previous results indicate that ethanol-induced Cyp2b10 expression was not mediated by CAR activation, functional mapping of the 5′ upstream region of the Cyp2b10 gene was performed to identify important regulators that may influence ethanol-induced Cyp2b10 expression. Reporter gene assays revealed that the …
WebApr 13, 2024 · From QR codes to credit card swipers, restaurants are now managing more tech than ever ... Gene Marks CPA Business Keynote Speaker, Author, Columnist, Business Owner Published Apr 13, 2024 ... WebNov 25, 2016 · Chronic ethanol treatment causes increased hepatic CYP2B10 expression inPparβ/δ +/+ mice but not in Pparβ/δ-/-mice. Nuclear and cytosolic localization of the …
WebUse Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed. Cyp2b10 - … WebA distal gene fragment, at about -2000 kb in CYP2B1, CYP2B2, and Cyp2b10, has been shown to be a phenobarbital-responsive enhancer independent of proximal promoter …
WebMar 27, 2024 · GeneCards is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and predicted human genes. The knowledgebase automatically integrates gene-centric data from ~150 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information. …
WebCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes … iprof cm1Webalso its ability to activate the Cyp2b10 gene, we will develop the hypothesis that CCRP determines both CAR-dependent and -independent gene expression in the livers. Materials and Methods Generation of the CCRP knockout mice A colony of CCRP global knockout B6; 129-Dnajc7, tm1Neg . (CCRP-/-or KO iprof centreWebApr 19, 2024 · When gene expression patterns were examined in liver, induction of Cyp2b10 and UGT1A1 gene expression was absent in hUGT1/Car −/− mice, confirming the role of CAR in activation of these genes ... iprof cmWebMar 21, 2024 · UGT2B10 (UDP Glucuronosyltransferase Family 2 Member B10) is a Protein Coding gene. Diseases associated with UGT2B10 include Crigler-Najjar Syndrome, … iprof cm2 geometrieWebCyp2b10cytochrome P450, family 2, subfamily b, polypeptide 10 [ Mus musculus(house mouse) ] Gene ID: 13088, updated on 26-Sep-2024 Download Datasets Gene Sequences (FASTA) Transcript sequences (FASTA) Protein sequences(FASTA) iprof cm2WebEthanol-induced Hepatic Cyp2b10 Expression Is Regulated by PPAR / -dependent Modulation of SP1 Activity—Because the previous results indicate that ethanol-induced Cyp2b10 expression was not mediated by CAR activation, functional mapping of the 5 upstream region of the Cyp2b10 gene was performed to identify important regulators … orc litigation holdWebMar 5, 2024 · Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 [ (house mouse)] Gene ID: 13088, updated on 5-Mar-2024 Summary Predicted to enable heat … iprof cm1 grammaire