Conditional false discovery rate
Webgeneralizing the false discovery rate of Banjamini and Hochberg [1]. In this article, we bring newer insight to the k-FDR considering a mixture model involving independent p-values before motivating the developments of some new procedures that control it. We prove the WebJul 20, 2024 · We introduce a new class of methods for finite-sample false discovery rate (FDR) control in multiple testing problems with dependent test statistics where the dependence is fully or partially known. Our approach separately calibrates a data-dependent p-value rejection threshold for each hypothesis, relaxing or tightening the threshold as …
Conditional false discovery rate
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WebJan 1, 2024 · Conditional False Discovery Rate Analysis Of Genome-Wide Association Studies Uncovers Genetic LOCI Shared Between Schizophrenia And Volumes Of … Web5.7.3 Validation. False discovery rates (false positives) are a major problem in proteomics and can be caused by: (1) the statistical process used to identify significant protein signal …
WebWe introduce a new class of methods for finite-sample false discovery rate (FDR) control in multiple testing problems with dependent test statistics where the dependence is fully or partially known. Our approach separately calibrates a data-dependent p-value rejection threshold for each hypothesis, relaxing or tightening the threshold as ... WebThis repository contains R functions to compute the 'Conditional False Discovery Rate', a method to analyse genome-wide association studies (GWAS) for related diseases originally proposed by Andreasson et al (2013), in the case where the two GWAS have shared controls.These functions widen the scope of the existing technique and enable improved …
WebNov 20, 2024 · Use of the conditional false discovery rate (cFDR) approach, which leverages pleiotropy identified from existing GWAS outputs, has been successful in discovering novel associated variants in related phenotypes. Here, genome-wide association study outputs for both von Korff chronic pain grade and for MDD were used to identify … WebJan 23, 2024 · The conditional false discovery rate (cFDR) The cFDR is an estimate of the posterior proba bility of a primary trait of non-G! E . interaction given p-value thresholds for hypothesis tests of G!
WebNov 17, 2024 · Conditional local false discovery rate; Covariate–assisted inference; Structured multiple testing; Time series anomaly detection; Supplementary material. The supplementary material contains the proofs of main theorems, other theoretical results and additional numerical results.
WebConditional calibration for false discovery rate control under dependence William Fithian and Lihua Lei July 17, 2024 Abstract We introduceanew classofmethodsforfinite-sample … coloring pages get well soon printable freeWebBoca SM, Leek JT. A direct approach to estimating false discovery rates conditional on covariates. PeerJ. 2024;2024(12):e6035. doi: 10.7717/peerj.6035 dr smiley\\u0027s funhouse gameWebApr 25, 2013 · For each nominal p-value, an estimate of the conditional False Discovery Rate (FDR) was obtained from the conditional empirical cdfs . Using this conditional FDR method, we constructed two … coloring pages giraffe printableWebThe conditional false discovery rate (cFDR) circumvents the difficulties of estimating PDFs by approximating the optimal ratio using cumulative density functions (CDFs) (Andreassen et al., 2013c). In this case, the covariate is generally a set of p‐values arising from an analogous procedure on the same variables for a second ‘conditional ... dr smiley\u0027s funhouse game downloadWebcfdr.pleio is an R package implementing conditional and conjunctional false discovery rates for studying pleiotropic gene variants between a pair of phenotypic traits. - GitHub - alexploner/cfdr.pleio: cfdr.pleio is an R package implementing conditional and conjunctional false discovery rates for studying pleiotropic gene variants between a pair of … coloring pages girls printableWebOne of these is a powerful nonparametric procedure called enhanced false discovery rate (EFDR). A drawback of EFDR is that it requires the data to be defined on regular pixels … coloring pages geometric designsWebJul 20, 2024 · Conditional calibration for false discovery rate control under dependence. We introduce a new class of methods for finite-sample false discovery rate (FDR) control in multiple testing problems with dependent test statistics where the dependence is fully or partially known. Our approach separately calibrates a data … coloring pages girl with umbrella